Dr. Smith's ECG Blog

Instructive ECGs in Emergency Medicine Clinical Content

Associate Editors:
— Pendell Meyers & Ken Grauer (2018)
— Jesse McLaren & Emre Aslanger (2022)
— Willy Frick (2024)

editors

New upright T-wave that is NOT pseudonormalization

A 79 yo female presented with crescendo angina. She has a history of anterior STEMI a few years ago treated with tPA. She has DM, HTN, and smokes. She was pain free at the time of this ECG (ECG #1):

There is one mm of ST elevation in each of V1-V3, along with deep
QS-waves and upright but not large or tall T-waves in V1-V3. This is
typical “LV aneurysm” morphology (otherwise known as persistent ST
elevation after old MI). This typically has a low T/QRS ratio..

It is always wise to compare with a previous ECG, but only with knowledge of the normal evolution of post-MI ECGs. Here are the previous ECGs:

ECG #2 is the last ECG, recorded after resolution of the previous anterior STEMI shown below.

T-waves are inverted and QS-waves are present. This is a typical ECG of post transmural MI, with shallow
T-wave inversion in right precordial leads V1-V3. Non-STEMIs have
deeper T-wave inversion and preservation of some R-wave, often a
QR-wave. (There is deeper T inversion in V4-V6.)

ECG #3 is the one obviously diagnostic of anterior STEMI (before evolution to the LV aneurysm morphology above:

Obvious anterior STEMI

Why are the T-waves upright now (ECG #1)? Is it pseudonormalization? No:

In the normal evolution (over months) of the post-MI ECG, T inversion (usually) becomes upright. On the other hand, pseudonormalization happens acutely (within the first week or two), usually after a reperfused MI and is due to re-occlusion. The T-waves are large and hyperacute.

Thus, we expect that the T inversion after an MI will be resolved if we get an ECG much later.

So ECG #1 is not due to pseudonormalization. If the patient has ongoing symptoms (unlike this one), serial ECGs are indicated because hyperacute T-waves and ST elevation may develop, but this ECG#1 represents the expected ECG evolution of this patient with previous transmural MI. This patient ruled out for MI by troponin.

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Here are examples of true pseudonormalization.

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Cardiac Arrest, Ventricular Fibrillation, Inferior and Right ventricular MI (RVMI) or "Pseudoanteroseptal MI"

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Anterior Hyperacute T-waves diagnostic of LAD Occlusion

View Comments (4)
  1. Dr Smith how often would you get serial EKG´s if the patient was symptomatic? q 10 min?
    Jorge Brenes, IM

  2. hi dr smith kindly can u answer my question why t wave upright although t wave represent repolarization and it moves from apex to base rather base to apex in case of depolarization thanks

  3. Steve Smith

    I'm sorry I don't understand the question. Please re-read the post, as I have edited and clarified it.

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